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Derived from events. Never edited by hand.

Leaderboard

Named model releases are the scoring unit. Families and organizations are rollups of those releases, including internal systems when a lab has not named the model.

RankModelOrganizationBenefitHarmNetEventsLast impact
1AlphaFold 3

AlphaFold

Google DeepMind+10.770.0010.7718 May 2024
2RFdiffusion

RoseTTAFold

University of Washington Institute for Protein Design+8.450.008.45111 Jul 2023
3AIFS

AIFS

European Centre for Medium-Range Weather Forecasts+3.680.003.68125 Feb 2025
4PaLM 2

PaLM

Google DeepMind+3.540.003.54114 Dec 2023
5AlphaGeometry

AlphaGeometry

Google DeepMind+2.770.002.77117 Jan 2024
6AlphaMissense

AlphaFold

Google DeepMind+2.650.002.65119 Sep 2023
7GraphCast

GraphCast

Google DeepMind+2.650.002.65114 Nov 2023
8ChatGPT

GPT

OpenAI+2.68−0.212.47222 Jun 2023
9GenCast

GraphCast

Google DeepMind+2.460.002.4614 Dec 2024
10OpenAI Codex

Codex

OpenAI+2.450.002.45121 Jun 2022
11GNoME

GNoME

Google DeepMind+2.380.002.38229 Nov 2023
12AlphaChip

AlphaChip

Google DeepMind+2.310.002.3119 Jun 2021
13Waymo Driver

Waymo Driver

Waymo+2.160.002.16120 Dec 2023
14ESM3

ESM

EvolutionaryScale+2.060.002.06116 Jan 2025
15Google Flood Forecasting Model

NeuralHydrology

Google+2.000.002.00120 Mar 2024
16OpenAI Internal Research System — 2026-09

GPT-6 · internal / unreleased

OpenAI+2.000.002.0028 Sep 2026
17AlphaGenome

AlphaGenome

Google DeepMind+1.980.001.98128 Jan 2026
18RoseTTAFold All-Atom

RoseTTAFold

University of Washington Institute for Protein Design+1.940.001.9417 Mar 2024
19MatterGen

MatterGen

Microsoft+1.740.001.74115 Jan 2025
20Pangu-Weather

Pangu

Huawei+1.730.001.7315 Jul 2023
21Evo

Evo

Arc Institute+1.670.001.67114 Nov 2024
22Profluent Protein Language Model

Profluent PLM

Profluent+1.670.001.67130 Jul 2025
23Aurora

Aurora

Microsoft+1.640.001.64121 May 2025
24NeuralGCM

NeuralGCM

Google DeepMind+1.560.001.56122 Jul 2024
25AlphaProof

AlphaProof

Google DeepMind+1.390.001.39125 Jul 2024
26Claude 3.7 Sonnet

Claude

Anthropic+1.370.001.37124 Feb 2025
27AlphaProteo

AlphaProteo

Google DeepMind+1.220.001.2215 Sep 2024
28codex-1

Codex

OpenAI+1.110.001.11116 May 2025
29AlphaDev

AlphaZero

Google DeepMind+0.960.000.9617 Jun 2023
30BindCraft

BindCraft

EPFL+0.890.000.89127 Aug 2025
31Gemini

Gemini

Google DeepMind+0.880.000.88114 May 2025
32Gemini Deep Think

Gemini

Google DeepMind+0.790.000.79121 Jul 2025
33OpenAI Internal Research Model — 2025-07

OpenAI reasoning models · internal / unreleased

OpenAI+0.740.000.74121 Jul 2025
34GPT-5.6 Sol

GPT-5.6

OpenAI+0.680.000.6818 Sep 2026
35GPT-6 Astra

GPT-6

OpenAI+0.600.000.6038 Sep 2026
36AlphaGeometry 2

AlphaGeometry

Google DeepMind+0.590.000.59125 Jul 2024
37Pharma.AI Internal Research Model

Pharma.AI · internal / unreleased

Insilico Medicine+0.580.000.5813 Jun 2025
38Boltz-1

Boltz

Massachusetts Institute of Technology+0.520.000.52119 Nov 2024
39AlphaFold 2

AlphaFold

Google DeepMind+0.510.000.51127 Aug 2025
40Claude

Claude · version unspecified

Anthropic+0.420.000.4228 Sep 2026
41GPT-4

GPT

OpenAI+0.400.000.4028 May 2024
42Literature NLP Recipe Model

Materials NLP

Lawrence Berkeley National Laboratory+0.370.000.37129 Nov 2023
43Chemprop Ensemble Internal Research Model

Chemprop · internal / unreleased

Massachusetts Institute of Technology+0.350.000.35120 Dec 2023
44AMIE

Gemini/PaLM medical

Google DeepMind+0.290.000.2919 Apr 2025
45Chai-1

Chai

Chai Discovery+0.280.000.28110 Oct 2024
46Evo 2

Evo

Arc Institute+0.240.000.24119 Feb 2025
47WeatherNext 2

GraphCast

Google DeepMind+0.240.000.24117 Nov 2025
48AlphaEarth Foundations

AlphaEarth

Google DeepMind+0.160.000.16130 Jul 2025
49Ganeshram–Duruisseaux–Anandkumar PINN

PINN

California Institute of Technology+0.120.000.1219 Sep 2026
50Chemprop-style Internal Research Model

Chemprop · internal / unreleased

Massachusetts Institute of Technology+0.080.000.08125 May 2023
51Green Light Traffic Model

Google Maps models

Google+0.070.000.07110 Oct 2023
52Gemini 2.0

Gemini

Google DeepMind+0.040.000.04119 Feb 2025
53Air Canada Website Chatbot

Unknown commercial chatbot

Air Canada0.00−0.11-0.11114 Feb 2024
54Tessa

Cass chatbot

National Eating Disorders Association0.00−0.12-0.12130 May 2023
55Grok

Grok

xAI0.00−0.24-0.2418 Jul 2025
56ElevenLabs Voice Model

ElevenLabs

ElevenLabs0.00−0.61-0.61121 Jan 2024
57Unknown Deepfake System

Unknown generative media models

Unknown0.00−0.84-0.84115 Jan 2024
58nH Predict

nH Predict

UnitedHealth Group0.00−1.26-1.26114 Nov 2023
59Character.AI Dialogue Model

Character.AI

Character.AI0.00−1.54-1.54128 Feb 2024
60Cruise ADS

Cruise autonomous driving system

Cruise0.00−3.08-3.0812 Oct 2023

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