AlphaFold 2

Benefit

+0.51

Harm

0.00

Net Good

0.51

Verified benefit

0.51

History

Cumulative score

Domains

Biology0.51

Release

Status released. First dated 15 Jul 2021.

Event timeline

Benefit27 Aug 2025

BindCraft designs nanomolar binders without high-throughput screening

EPFL-led BindCraft, published in Nature on 27 August 2025, used AlphaFold2 weights to design binders with 10–100 percent experimental success across diverse targets, including allergen, Cas9, toxin, and AAV applications.

BiologyverifiedTier 3 Major+0.51