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Anthropic

Claude

A family is a named generation or product line. Scores below are the sum of its named releases and any documented internal systems in the same line.

Benefit

+12.16

Harm

−4.76

Net Good

7.40

Releases

Leaderboard

RankModelOrganizationBenefitHarmNetEventsLast impact
7Anthropic Internal Research Model — 2026-08

Claude · internal / unreleased

Anthropic+5.060.005.06110 Aug 2026
30Claude 3.7 Sonnet

Claude

Anthropic+1.39−0.021.37526 Oct 2026
32Anthropic Claude Science Internal Research Model — Scorpion Binder Campaign (2026)

Claude · internal / unreleased

Anthropic+1.220.001.22120 Oct 2026
35Claude Fable 5

Claude

Anthropic+1.120.001.12431 Aug 2026
49Claude

Claude · version unspecified

Anthropic+3.30−2.980.32927 Oct 2026
68Anthropic Internal Research Test Model — 2026

Claude · internal / unreleased

Anthropic0.00−0.23-0.23130 Jul 2026
69Claude Opus 4.6

Claude

Anthropic0.00−0.23-0.23130 Jul 2026
72Claude Opus 4.7

Claude

Anthropic+0.08−0.56-0.48218 Sep 2026
73Claude Mythos 5

Claude

Anthropic0.00−0.76-0.76230 Jul 2026

Timeline

  • Benefit
  • Harm
  • Net
024681012202420252026

Events

Benefit27 Oct 2026

Claude-orchestrated Divergence Labs campaign produces experimental IgE-disruptor VHH hits

On 27 October 2026 Anthropic and Divergence Labs reported a Claude-directed campaign that generated about 35,000 VHH designs toward a biparatopic IgE disruptor for food allergy. Competitive BLI found 20/91 disruptor hits, three of which removed more soluble IgE than omalizumab at 25–400 nM, plus three de novo anchors. The arms have not been paired, cells and animals were not tested, and the designs did not beat parent sdAb026 at controlled doses.

BiologyprovisionalTier 3 Major+0.72
Benefit26 Oct 2026

Tradeoff-Aware Territory Design: A Multi-Objective Decision System for Enterprise Customer-to-Seller Allocation

arXiv:2610.31701v1 Announce Type: new Abstract: Enterprise customer journeys are shaped not only by product experiences and marketing, but also by recurring resource-allocation decisions. In B2B go-to-market (GTM) organizations, territory carving determines which accounts receive seller coverage, which seller-account relationships are preserved, and how limited field capacity is distributed. Yet the process often remains manual, making it difficult to compare opportunities, value continuity, and evaluate tradeoffs among growth, balance, capacity, and feasibility. We present a production dec

BiologyprovisionalTier 1 Useful+0.04
Benefit20 Oct 2026

Claude research campaign produces 17 experimentally validated scorpion-toxin binders

Anthropic reports that an unreleased Claude Science model generated 318,484 protein designs in 64 hours; external labs tested 211 and 17 met strict binding criteria against individual scorpion toxins. No venom neutralization or antivenom has been demonstrated.

BiologyprovisionalTier 3 Major+1.22
Harm24 Sep 2026

Australia PM Albanese says OpenAI agent breached government website in June - Reuters

Australia PM Albanese says OpenAI agent breached government website in June  Reuters

SafetyprovisionalTier 1 Limited Harm−0.03
Benefit18 Sep 2026

What Do Current Systematic Generalization Tasks Miss? A Reasoning-Centered Analysis

arXiv:2609.19212v1 Announce Type: new Abstract: Systematic generalization, the ability to solve novel problems by recombining known atomic elements, is central to human intelligence but difficult to study rigorously under controlled settings. Existing studies therefore rely on simplifications such as approximately linear action composition, productivity-based tests, and action-explicit goals, which make systematic generalization easier to study but omit some essential aspects of this capability. To characterize what these simplifications miss, we adopt a reasoning-centered lens and introduce

BiologyprovisionalTier 1 Useful+0.08
Benefit17 Sep 2026

Collaborative Memory for Multi-Agent VLM Systems

arXiv:2609.17921v1 Announce Type: new Abstract: Vision-language model (VLM) agents combine specialized perception, tools, and reasoning to address complex visual tasks. In multi-agent settings, different agents inspect different image regions, video frames, or visual representations, so collaboration extends beyond distributed reasoning to distributed perception. This makes shared visual context a central problem in VLM agent collaboration. In this paper, we frame memory hierarchy, cross-agent sharing, and consistency mechanisms around the need to reconcile interpretations and update dependen

OtherprovisionalTier 1 Useful+0.00
Benefit17 Sep 2026

From Prompt to Pipeline: A Comparative Evaluation of Large Language Model Coding Agents for Reproducible Bioinformatics Pipeline Construction

Agentic coding systems are increasingly presented as a way to reduce the engineering burden of scientific software development. Bioinformatics is a strong test case for this claim because useful pipelines must combine domain-specific analysis choices, command-line software, sample metadata, workflow orchestration, container or HPC execution, and interpretable quality-control reporting. We evaluated three agentic systems - Biomni, Claude Code, and Codex - on the same task: constructing a Nextflow DSL2 pipeline for paired-end CUT&Tag data that included read QC, trimming, alignment, filtering, du

BiologyprovisionalTier 1 Useful+0.00
Harm10 Sep 2026

Russian-nexus operators use Claude to run espionage against Ukraine and European targets

Anthropic’s September 2026 threat report describes GTG-20006, a Russian-speaking actor it links to Midnight Blizzard tradecraft, using Claude-driven workflows to phish, persist, and exfiltrate data from more than 20 organizations concentrated in Ukraine and Europe, including government, diplomatic, and drone-supply-chain victims.

SafetyprovisionalTier 3 Major Harm−0.96