{"data":{"event":{"id":"d84b4e4a-be80-4bdb-8975-56d9a0c06dc6","slug":"boltz-1-open-af3-replica","title":"Boltz-1 releases an MIT-licensed AlphaFold 3–level complex predictor","short_summary":"MIT Jameel Clinic researchers released Boltz-1 in November 2024 as a fully open biomolecular complex model with training code, claiming AF3-level accuracy and an inference-time steering method.","full_description":"The bioRxiv paper described architecture and data-processing choices aimed at matching commercial AF3-class accuracy while publishing weights, training code, and datasets under MIT. Boltz-steering was proposed to reduce implausible poses. Subsequent Boltz versions followed. Independent benchmarks generally treat Boltz as a leading open alternative rather than a proven universal winner.","ledger_type":"benefit","primary_domain_id":"8f1af1b9-7302-4b51-aae9-fdfac04d158a","event_status":"verified","event_date":"2024-11-19T00:00:00.000Z","discovery_date":"2024-11-19T00:00:00.000Z","first_published_date":"2024-11-19T00:00:00.000Z","last_reviewed_date":"2024-11-19T00:00:00.000Z","geographic_scope":"Global open-source structural biology","affected_population":"Researchers who cannot use closed AF3 weights","base_impact_tier":2,"base_score":"3.00","attribution_multiplier":"0.9000","evidence_multiplier":"0.5000","realization_multiplier":"0.7000","durability_multiplier":"0.5500","current_event_score":"0.519800","confidence_level":"high","score_explanation":"Notable democratization of AF3-class modeling (tier 2). High attribution. Preprint plus rapid community use (0.50). Realization is widely installed software. Medium durability as versions increment.","methodology_version_id":"d7881163-fb23-4e71-8625-bac1a8662c0f","original_methodology_version_id":"d7881163-fb23-4e71-8625-bac1a8662c0f","published_at":"2024-11-19T00:00:00.000Z","created_at":"2026-09-13T20:47:20.075Z","updated_at":"2026-09-13T20:47:20.075Z","flags":[],"domain_name":"Biology","domain_slug":"biology","methodology_version":"0.1"},"contributions":[{"id":"4abfa57a-1ae9-4641-a3fd-fc9bb8dcbd11","event_id":"d84b4e4a-be80-4bdb-8975-56d9a0c06dc6","model_id":"bb116c0a-c431-4892-8e2a-5cbc6ecb0021","role_description":"Open-source biomolecular complex predictor.","attribution_multiplier":"0.9000","credit_share":"1.0000","contribution_score":"0.519800","attribution_rationale":"The released model is the contribution.","attribution_confidence":"medium","first_used_date":"2024-11-19T00:00:00.000Z","model_version_if_known":null,"review_status":"approved","created_at":"2026-09-13T20:47:20.075Z","model_slug":"boltz-1","model_name":"Boltz-1","identity_class":"named_release","is_internal":false,"family_name":"Boltz","family_slug":"mit-boltz","organization_name":"Massachusetts Institute of Technology","organization_slug":"mit"}],"sources":[{"id":"e906dc11-03b1-4809-9210-e1d21b11aea6","event_id":"d84b4e4a-be80-4bdb-8975-56d9a0c06dc6","url":"https://www.biorxiv.org/content/10.1101/2024.11.19.624167v1","canonical_url":"https://www.biorxiv.org/content/10.1101/2024.11.19.624167v1","source_type":"preprint","publisher":"bioRxiv","author":null,"publication_date":"2024-11-20T00:00:00.000Z","retrieved_at":"2026-09-13T20:47:20.075Z","title":"Boltz-1 Democratizing Biomolecular Interaction Modeling","excerpt":null,"content_hash":null,"source_reliability_class":"low","is_primary_source":true,"is_independent":false,"is_peer_reviewed":false,"archived_url":null,"created_at":"2026-09-13T20:47:20.075Z"}],"claims":[{"id":"70a7f0de-bd2b-4303-aa3c-283bbe48a3cf","event_id":"d84b4e4a-be80-4bdb-8975-56d9a0c06dc6","claim_text":"Boltz-1 was released with open training and inference code and reported AF3-comparable complex accuracy.","claim_type":"outcome","claim_status":"supported","confidence_score":null,"created_at":"2026-09-13T20:47:20.075Z","updated_at":"2026-09-13T20:47:20.075Z"}],"revisions":[{"id":"1ef1c93d-1066-4d78-83f8-7ea8edffeaa5","event_id":"d84b4e4a-be80-4bdb-8975-56d9a0c06dc6","model_id":null,"previous_score":"0.000000","new_score":"0.519800","previous_factors":{},"new_factors":{"evidence":0.5,"base_score":3,"durability":0.55,"attribution":0.9,"realization":0.7},"change_reason":"Initial adjudicated seed score under methodology 0.1.","trigger_type":"seed","trigger_source_ids":null,"reviewer_id":null,"review_status":"published","created_at":"2026-09-13T20:47:20.075Z"}],"secondary":[{"name":"Computer Science","slug":"computer-science"}]},"methodology_version":"0.1"}