{"data":{"event":{"id":"23f1e928-b8db-4251-9785-dd5b9ed54787","slug":"alphagenome-regulatory-variant-prediction","title":"AlphaGenome predicts multimodal regulatory effects of DNA variants","short_summary":"DeepMind’s AlphaGenome takes up to 1 Mb of DNA and predicts gene expression, splicing, chromatin, and contact tracks, matching or beating external models on 25 of 26 variant-effect tests in a 28 January 2026 Nature paper.","full_description":"Announced in 2025 and peer-reviewed in 2026, AlphaGenome unifies long-context sequence input with base-resolution multimodal outputs. The authors showed it can recover mechanisms of known TAL1 oncogene variants and released APIs for research. It is not a clinical genome interpreter. 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